Portrait of Dr Farideh Javid Dr Farideh Javid

fajavid@hud.ac.uk | 01484 472543


Farideh was offered a Senior Lectureship in Pharmacology at the University of Huddersfield in June 2008. Following her first degree in Chemistry with First Class Honors at the University of Tehran, she then completed an MSc programme in Pharmacology with Distinction at the School of Pharmacy in the University of Bradford. In 1996 she started a PhD research project at the same school in the University of Bradford. Her PhD project was on the neuropharmacological investigation of drugs- and motion-induced emesis and changes in the gastrointestinal motility. Following completion of her PhD studies in 1999, she was employed in various posts at the University of Bradford, including Research Fellow and then Lecturer. During this time she successfully supervised various PhD programmes and also became a Fellow of the Higher Education Academy prior to her move to Huddersfield. She holds several patents as a result of her collaboration with industry. She developed the Pharmacology modules for the MPharm course at the University of Huddersfield for years 1, 2 and 3 and her on-going research programmes focus on identifying and investigating the mechanism of actions of novel drugs in cancer Pharmacology. Her ultimate aim is to develop novel drugs for cancer patients. 

Research and Scholarship

My research interests focus on how disease processes or abnormalities modify the function of the gastrointestinal tract and also the mechanisms of actions of drugs affecting this system. There is a special interest in establishing the precise involvement and interaction between central and peripheral serotonergic, cannabinoids, neurokinin and other peptidergic systems relevant to significant therapeutic advances in gastrointestinal disorders such as irritable bowel syndrome (IBS) and/or inflammatory bowel disease (IBD).

I have also been involved in a research collaboration with the GW Pharmaceuticals to investigate the anti-cancer effects of non-psychoactive cannabinoids on a variety of tumour cells. Further research are under way to also investigate the anti-inflammatory actions of phytocannabinoids and other herbal medicine.

In summary my Research Interests are:

  1. Gastrointestinal motility
  2. E-coli-induced Diarrhoea
  3. Development of cell culture models to investigate inflammatory processes and identifying novel anti-inflammatory agents
  4. Identifying novel therapeutics with anti-cancer activity
  5. Pharmacology of cannabinoids and Herbal Medicine

Publications and Other Research Outputs


Kumar, R., Siril, P. and Javid, F. (2016) ‘Unusual anti-leukemia activity of nanoformulated naproxen and other non-steroidal anti-inflammatory drugsMaterials Science and Engineering: C , 69, pp. 1335-1344. ISSN 0928-4931

Sefat, F., Youseffi, M., Khaghani, S., Soon, C. and Javid, F. (2016) ‘Effect of Transforming Growth Factor-?3 on mono and multilayer chondrocytesCytokine , 83, pp. 118-126. ISSN 1043-4666

Javid, F (2016) ‘Take note Matt LeBlanc: here’s the scientific way to beat car sicknessThe Conversation . ISSN 2044-5032

Javid, F., Phillips, R., Afshinjavid, S., Verde, R. and Ligresti, A. (2016) ‘Cannabinoid pharmacology in cancer research: A new hope for cancer patients?European Journal of Pharmacology . ISSN 0014-2999

Hemming, K., Blackburn, J., Molyneux, G., Pitard, A., Rice, C., Page, M., Afshinjavid, S., Javid, F., Coles, S. and Horton, P. (2016) ‘Synthesis, Conformation and Antiproliferative Activity of Isothiazoloisoxazole 1,1-dioxidesOrganic and Biomolecular Chemistry , 14, pp. 2134-2144. ISSN 1477-0539


Makanjuola, S., Ayodele, S., Javid, F., Obafunwa, J., Oludara, M. and Popoola, A. (2014) ‘Breast cancer receptor status assessment and clinicopathological association in Nigerian women: A retrospective analysisJournal of Cancer Research & Therapy , 2 (8), pp. 122-127. ISSN 20524994

Mashhadi, F., Naylor, R. and Javid, F. (2014) ‘The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small IntestineGene Cell Tissue , 1 (1), p. e18311. ISSN 2345-6833

Javid, F. and Palea, S. (2014) ‘The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinusEuropean Journal of Pharmacology , 723, pp. 489-493. ISSN 0014-2999


Bolognini, D., Rock, E., Cluny, N., Cascio, M., Limebeer, C., Duncan, M., Stott, C., Javid, F., Parker, L. and Pertwee, R. (2013) ‘Cannabidiolic acid enhances 5-HT1A receptor activation and prevents vomiting in Suncus murinus and nausea-like behaviour in rats with greater potency and selectivity than cannabidiolBritish Journal of Pharmacology , 168 (6), pp. 1456-1470. ISSN 0007-1188

Javid, F., Bulmer, D., Broad, J., Aziz, Q., Dukes, G. and Sanger, G. (2013) ‘Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptorsEuropean Journal of Pharmacology , 699 (1-3), pp. 48-54. ISSN 0014-2999


Afshinjavid, S., Phillips, R. and Javid, F. (2012) ‘The effect of GWP42006, a cannabinoid extract on MCF-7 human breast carcinoma cells’. In: 6th European Congress of Pharmacology (EPHAR 2012), 17th – 20th July 2012, Granada, Spain , p. 496

Afshinjavid, S., Cluny, N., Okeke, I. and Javid, F. (2012) ‘The effect of Enteroaggregative escherichia coli (eaec) on 5-Hydroxytryptamine (5-HT), carbachol and electrical field stimulation (EFS)-induced contraction in the rat ileumpA2 Online , 10 (3), p. 350. ISSN 1741-1149


Batista Lobo, S., Denyer, M., Britland, S. and Javid, F. (2011) ‘The Involvement of the Serotonergic Transmission System in Neonatal and Adult Rat Ileum Contractility Varies with AgePharmacology , 88 (3-4), pp. 225-232. ISSN 0031-7012

Cluny, N., Naylor, R., Whittle, B. and Javid, F. (2011) ‘The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinusArchives of Pharmacal Research , 34 (9), pp. 1509-1517. ISSN 0253-6269

Javid, F., Afshinjavid, S., Phillips, R., Stott, C. and Ayerakwa, L. (2011) ‘The effect of CBD(BDS) botanical cannabinoid extraction on MCF-7 human breast carcinoma cells.’. In: 21st Annual Symposium of the International Cannabinoid Research Society 2011. Pheasant Run, St Charles Illinois, USA: International Cannabinoid Research Society. p. 120. ISBN 978-0-9786040-6-6


Farajian-Mashradi, F., Naylor, R. and Javid, F. (2010) ‘The effect of fluoxetine on electrical field stimulation-induced responses in the isolated rat small intestineMethods and Findings in Experimental and Clinical Pharmacology , 32 (9), pp. 645-656. ISSN 0379-0355

Javid, F (2010) ‘The effects of 5-HT and electrical field stimulation (EFS) in the bladder of suncus murinus’. In: WorldPharma, July 17th-22nd, Copenhagen

Lobo, S., Denyer, M. and Javid, F. (2010) ‘Intestinal model of Inflammation in primary cells’. In: Inflammation conference, 27-30th January 2010, Luxembourg


Soon, C., Youseffi, M., Blagden, N., Lobo, S., Javid, F. and Denyer, M. (2009) ‘Characterisation and biocompatibility study of nematic and cholesteric liquid crystals’. In: Medical Physics and Biomedical Engineering World Congress 2009, Sept 7-12, 2009, Munich, Germany

Khaghani, S., Denyer, M., Youseffi, M., Lobo, S. and Javid, F. (2009) ‘Effect of transforming growth factor-beta (TGF-?1) in biological regulation of primary chondrocyte’. In: 15th International Biomedical Science and Technology Symposium, 16 - 19 August 2009, Cyprus

Khaghani, S., Denyer, M., Youseffi, M., Lobo, S. and Javid, F. (2009) ‘Purification of Primary Chondrocyte Cells extracted from knee joint of Sprague-Dawley rats’. In: The Anatomical Society Winter Meeting, 6th-8th January 2009, Oxford, UK


Javid, F. and McCurrie, J. (2008) Clinical Physiology and Pharmacology: The Essentials . London, UK: Wiley Blackwell. ISBN 978-0-470-51852-6

Lobo, S., Denyer, M., Gopalan, R. and Javid, F. (2008) ‘Technique for cryopreservation of intestinal smooth muscle cellsCryobiology , 57 (2), pp. 186-189. ISSN 00112240

Cluny, N., Naylor, R., Whittle, B. and Javid, F. (2008) ‘The Effects of Cannabidiol and Tetrahydrocannabinol on Motion-Induced Emesis in Suncus murinusBasic and Clinical Pharmacology and Toxicology , 103 (2), pp. 150-156. ISSN 17427835

Jamil, M., Sefat, F., Khaghani, S., Batista Lobo, S., Javid, F., Youseffi, M., Britland, S., Liu, S., See, C., Somekh, M. and Denyer, M. (2008) ‘Cell imaging with the widefield surface plasmon microscope’. In: 4th Kuala Lumpur International Conference on Biomedical Engineering 2008. Berlin: Springer. pp. 528-531. ISBN 1680-0737


Batista Lobo, S., Denyer, M., Britland, S. and Javid, F. (2007) ‘Development of an intestinal cell culture model to obtain smooth muscle cells and myenteric neuronesJournal of Anatomy , 211 (6), pp. 819-829. ISSN 00218782


Javid, F (2006) ‘The effect of the 5-HT1A receptor agonist, 8-OH-DPAT, on motion-induced emesis in Suncus murinusPharmacology Biochemistry and Behavior , 85 (4), pp. 820-826. ISSN 00913057


Javid, F (2002) ‘The effect of serotonin and serotonin receptor antagonists on motion sickness in Suncus murinusPharmacology Biochemistry and Behavior , 73 (4), pp. 979-989. ISSN 00913057


Javid, F (2001) ‘Opioid receptor involvement in the adaptation to motion sickness in Suncus murinusPharmacology Biochemistry and Behavior , 68 (4), pp. 761-767. ISSN 00913057


Javid, F (1999) ‘Characterisation of 5-HT2 receptor subtypes in the Suncus murinus intestineEuropean Journal of Pharmacology , 381 (2-3), pp. 161-169. ISSN 00142999

Javid, F (1999) ‘Variables of Movement Amplitude and Frequency in the Development of Motion Sickness in Suncus murinusPharmacology Biochemistry and Behavior , 64 (1), pp. 115-122. ISSN 00913057

Javid, F. and Naylor, R. (1999) ‘Characterization of the 5-hydroxytryptamine receptors mediating contraction in the intestine of Suncus murinusBritish Journal of Pharmacology , 127 (8), pp. 1867-1875. ISSN 0007-1188

Research Degree Supervision

Cannabinoid research

  1. To investigate the role of cannabinoid receptors in the inflammatory processes.
  2. To investigate the potential of cannabinoids, in particular phytocannabinoids, as novel anti-cancer drugs.

Gastrointestinal Motility Research

To investigate the mechanism of action of pathogens such as Enteroaggregative Escherichia coli (EAEC) and C.difficile on the gastrointestinal tract. Would Cannabinoids provide a solution?

The proposed project is designed to study the neuronal circuitry and the neurotransmitters involved in EAEC or C.difficil-induced diarrhoea within the enteric nervous system in rodents and human tissues. The objectives will be achieved by continuing with conventional pharmacological studies together with molecular and biochemical studies into the mechanisms and treatment of disturbed pattern of gastrointestinal motility. Such studies will also focus on investigating the role of CB receptors in inflammatory responses of gastrointestinal tract. Such studies will be designed to investigate the mechanism of actions of non-psychoactive cannabinoids such as CBD, CBDA and THCA, and perhaps some other synthetic agonists in normal and diseased epithelial cells.

Herbal Medicine

  1. To investigate the anti-inflammatory potential of herbal extracts
  2. To investigate the anti-tumour activity of herbal extracts

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